Panini's

Panini's Panini's restaurant is located in the heart of Downtown Syracuse, located on Harrison Street. We of

Permanently closed.

Breakfast, Coffee, Lunch, Paninis, Soups, Sandwiches, Salads

04/10/2026

As we enter our last day of business, I have to thank everyone for the many kind words and encouragement for myself and staff. I can say that I will miss the many, many fantastic people I have had the honor to serve over 11 years.
I thank my family for taking the ride with me, as I lived my dream, and for the many sacrifices they made over the years. Thank you for all your love and support.
Many have asked what is next?

For myself, I say time will tell.

For Panini's, well, stay tuned!!!

Many thanks, Steve

04/06/2026

We will be closed for the day on Monday, 4/6. We will reopen on Tuesday, 4/7.

04/05/2026

🔗 https://l.syracuse.com/nuq1d8

Panini’s, located at 222 Harrison St. next to Ale ‘n’ Angus, announced its final day of service will be Friday, April 10.

“After many unforgettable meals, conversations, and shared moments, we will be closing our doors,” the store posted on Facebook. “From the bottom of our hearts, thank you.”

Tap the link above for the full story.

03/31/2026

To Our Valued Guests and Community,

After many unforgettable meals, conversations, and shared moments, we will be closing our doors, with our final day of service on Friday, April 10th.

From the bottom of our hearts, thank you. Your support, your loyalty, and your kindness have meant more to us than we can express. Whether you visited once or became part of our extended family, you helped make this place what it is.

We are deeply grateful for the opportunity to serve downtown Syracuse for 11 years and be part of this community. It has truly been an honor.

With appreciation and warmest thanks,
The Panini’s Owner’s and Staff

03/23/2026

We will be closed Monday, 3/23. We apologize for the inconvenience. We will reopen on Tuesday, 3/24.

02/23/2026

Panini’s is officially back open this week starting at 8am today. Thank you for your patience, and we look forward to seeing you!

02/20/2026

We are finishing final clean up and are happy to say we will be reopening on Monday, 2/23.
We appreciate your patience and understanding and hope to see you soon.

02/16/2026

We are still working on getting back open due to flood damage. We appreciate your understanding and hope to see you soon.

02/10/2026

📢 Important Update from Paninis.org

Due to significant flooding in our building and restaurant, we will be closed starting tomorrow, 2/11, until further notice. Our team is working hard to assess the situation and will share an update when we are able.

Thank you for your patience, understanding, and continued support during this unexpected disruption.

12/30/2025

❄️ Weather Update & Holiday Hours ❄️

Due to the winter storm and current travel advisory, Paninis will be closed today, 12/30

A quick reminder:
We will also be closed 12/31–1/2 for the New Year’s holiday.

We look forward to welcoming you back when we reopen on Monday, 1/5. Stay warm, stay safe, and enjoy the start of the new year!

12/23/2025

🎄 Happy Holidays from the team at Panini's! 🎄
As we wrap up the year, we want to thank all of our wonderful customers for your support and smiles throughout the season.

Please note our special holiday hours:
✨ Closed for Christmas: 12/24 – 12/26
✨ Open: 12/29 & 12/30
✨ Closed for New Year’s: 12/31 – 1/2

We look forward to serving you again soon. Wishing you a warm, joyful, and delicious holiday season!

11/26/2025

🍂🦃 Happy Thanksgiving! 🦃🍂
This season, we are especially thankful for YOU—our wonderful customers who make what we do so meaningful.

In observance of the holiday, we will be closed on Thursday, 11/27 and Friday, 11/28. We’ll reopen with regular hours on Monday, 12/1.

Wishing you a warm, joyful, and safe Thanksgiving filled with family, friends, and plenty of good food! 🧡

Address

222 Harrison Street
Syracuse, NY
13202

Telephone

+13154716464

Website

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