Santee Seafood Bistro

Santee Seafood Bistro A small intimate restaurant offering a variety of seafood, southern comfort food and spirits.

small intimate seafood restaurant where you can either dine-in, take-out, and/or purchase raw seafood (market is seasonal)

Dive into a delicious shrimp po' boy with crispy fries and fresh coleslaw on the side. 🌟
09/07/2026

Dive into a delicious shrimp po' boy with crispy fries and fresh coleslaw on the side. 🌟

Crispy fried fish with golden fries and coleslaw offers a comforting taste of home-style goodness. 🐟
09/05/2026

Crispy fried fish with golden fries and coleslaw offers a comforting taste of home-style goodness. 🐟

Enjoying a meal together just feels right. Let our team serve up your favorite comfort food in an inviting atmosphere—pe...
09/04/2026

Enjoying a meal together just feels right. Let our team serve up your favorite comfort food in an inviting atmosphere—perfect for sharing good moments and easy conversation. Save your seat now!

Enjoy a comforting plate of tender fish fillets and greens that feel just like home. ✨
09/03/2026

Enjoy a comforting plate of tender fish fillets and greens that feel just like home. ✨

Creamy shrimp pasta with a side of golden toast offers a delightful taste of comfort and warmth. 🍴
09/01/2026

Creamy shrimp pasta with a side of golden toast offers a delightful taste of comfort and warmth. 🍴

Savor the comforting taste of tender greens and perfectly cooked fish in a cozy setting.
08/30/2026

Savor the comforting taste of tender greens and perfectly cooked fish in a cozy setting.

Celebrate your wedding, birthday, or corporate event with us in Santee! Enjoy delicious seafood and a welcoming atmosphe...
08/28/2026

Celebrate your wedding, birthday, or corporate event with us in Santee! Enjoy delicious seafood and a welcoming atmosphere. We also cater to other event types. Contact us to plan your unforgettable party!

Creamy shrimp pasta paired with toasted bread offers a delightful taste of comfort and warmth.
08/26/2026

Creamy shrimp pasta paired with toasted bread offers a delightful taste of comfort and warmth.

Special thanks to these beautiful ladies from Sumter county. Mrs. Deloris Ramsey Hunter Stephenson and friends heard of ...
08/25/2026

Special thanks to these beautiful ladies from Sumter county. Mrs. Deloris Ramsey Hunter Stephenson and friends heard of the business and decided to drive "over the water" and decided to dine with us. We appreciate you and we wish the birthday beauty many many more 🎂
/RamseyFamilyfriend

Enjoy a delicious fried fish plate with seasoned rice and a dash of lemon zest. 🍋
08/24/2026

Enjoy a delicious fried fish plate with seasoned rice and a dash of lemon zest. 🍋

Address

648 Bass Drive
Santee, SC
29142

Opening Hours

Tuesday 11:30am - 8:30pm
Wednesday 11:30am - 8:30pm
Thursday 11:30am - 8:30pm
Friday 11:30am - 8:30pm
Saturday 11:30am - 8:30pm
Sunday 11:30am - 4pm

Telephone

+18038544840

Website

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