221 Main - Restaurant & Cocktail House

221 Main - Restaurant & Cocktail House Welcome to 221 Main - Restaurant & Cocktail House an award-winning steakhouse in the heart of St. Joseph, MI. Voted #1 steakhouse in St. Joe! Prime rib every Sat.
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Hand-cut steaks w/our famous zip sauce! Since 2012, we have been delighting diners with our delicious steaks, seafood dishes, burgers, and an extensive selection of wines, craft cocktails, and draft beers. Beyond our exceptional menu, we also offer event space rentals, catering services, private dining options, and convenient takeout for those craving our delectable dishes at home. Come experience

the perfect blend of culinary excellence and warm hospitality at 221 Main - where every meal is an unforgettable experience. Stop by today! Services:
Weddings
Rehearsal Dinners
Private Dining
Event Catering
Takeout
Customizable Event Menus
Bar Service
Event Space Rental
Outdoor Seating
Waitlist Management
Catering
Seasonal Menus
Event Hosting
Corporate Catering
Coffee Bar
Sustainable Packages
Online Reservations
Brunch
Breakfast

Specialties:
Award Winning Steakhouse and Cocktail Lounge
The Terrace
Copper Pot Breakfast Cafe
The Largest Whiskey In The State
335 Whiskeys From Around The World
Delicious Seafood
Parmesan Encrusted Whitefish
Child-Friendly
Gluten-Free Options

Products:
Surf and Turf
Filet Mignon
Shrimp
Garlic Ribeye
Steak Fries
Roasted Whitefish
Blackened Salmon
Lake Perch
Seafood Pasta
Short Ribs
Sirloin
Steakhouse Burgers
Chicken Marsala
Eggs Benedict
Bloody Marys
Wines
Draft Beers
Craft Cocktails
Champagne
Prosecco


A dinner destination! Serving appetizers like flash-fried Brussels Sprouts, Firecracker Shrimp or our homemade spinach artichoke dip. Salads include our huge Wedge or an amazing Grilled Caesar with homemade dressing. Hungry for a burger? Try our Comeback Burger - the special sauce is amazing! Our steaks are where we make our mark. We have several different cuts from which to choose, and you can pair any of our steaks with a cold-water lobster tail for a delicious Surf-n-Turf dinner. The Braised Short Ribs are so tender, you don't even need a knife!
221 also offers plenty of seafood options. Our Seafood Pasta is amazing but the Parmesan Crusted Whitefish is our #1 seller and will keep you coming back for more. Other menu features include the Double-Bone Pork Chop with apple butter, Duck Breast with Michigan cherry gastrique, the Chicken Marsala is always a top-seller and our Mac & Cheese is perfect for those looking for some comfort food. Finish the evening with one of our desserts: homemade crème brûlée, giant NY-style cheesecake, flourless chocolate torte or our ever-popular hot cookie sundae! And don't forget our cocktails & whiskey list! 221 Main makes some of the best cocktails in SW Michigan and we have over 335 whiskies from all around the world for you to try! CHEERS!

06/08/2026

ARE YOU 17+ LOOKING FOR A SUMMER JOB?
221 Main is hiring hosts! Email [email protected] (or stop in Wed-Sun) to set up an interview. Thanks!

06/05/2026
The Terrace and the plaza are both open tonight! It’s perfect weather for dining outside. Oysters on the Half… Summer Sc...
06/03/2026

The Terrace and the plaza are both open tonight! It’s perfect weather for dining outside. Oysters on the Half… Summer Scallops… Strawberry 75… Come join us at 221 Main.

Let’s celebrate the new summer menu at 221! Cauliflower Steak, Duck Breast, Strawberry 75 and more. Outdoor dining on BO...
05/30/2026

Let’s celebrate the new summer menu at 221! Cauliflower Steak, Duck Breast, Strawberry 75 and more. Outdoor dining on BOTH floors. Reservations at 221stjoe.com

🚨🚨HAMSTER!!🚨🚨 😂TONIGHT ONLY AT 221: give the password when seated and get $6 Martinis, Cosmos, Old Fashions and more. Ma...
05/28/2026

🚨🚨HAMSTER!!🚨🚨 😂
TONIGHT ONLY AT 221: give the password when seated and get $6 Martinis, Cosmos, Old Fashions and more. Martini Night is over for the summer, but if you say “HAMSTER” when you come in, we’ll break out the Martini Night menu JUST FOR YOU. Why “hamster”? Because it’s weird enough that you’d only know it by seeing this post. But this is TONIGHT ONLY so DON’T MISS OUT!

Smoked Pecan Old Fashioned!
05/27/2026

Smoked Pecan Old Fashioned!

HAPPY HUMPDAY!! Join us tonight at 221 for the final HAPPY HOUR before the summer season…$2 OFF ALL APPETIZERS $2 OFF AL...
05/27/2026

HAPPY HUMPDAY!! Join us tonight at 221 for the final HAPPY HOUR before the summer season…
$2 OFF ALL APPETIZERS
$2 OFF ALL COCKTAILS
$2 OFF ALL WINE
$2 OFF ALL WHISKIES
(even the top shelf stuff!)
ALL NIGHT TONIGHT AT 221.

Address

221 Main Street
Saint Joseph, MI
49085

Opening Hours

Wednesday 4:30pm - 8:30pm
Thursday 4:30pm - 8:30pm
Friday 4:30pm - 9pm
Saturday 4:30pm - 9pm
Sunday 4:30pm - 8:30pm

Telephone

+12699824000

Website

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