M Brothers at Mayo

M Brothers at Mayo Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from M Brothers at Mayo, Restaurant, 14335 Hospital Drive Suite 100, Jacksonville, FL.

M Brothers is a Medure Brothers Culinary Concept located in the Cannady Building Atrium at Jacksonville's Mayo Clinic, open to the public and offering a full-service dining experience.

Culinary Passport is our signature dinner series at M Brothers, inviting you to explore the flavors, traditions, and sto...
09/01/2026

Culinary Passport is our signature dinner series at M Brothers, inviting you to explore the flavors, traditions, and stories of a different destination each month.

✈️ Next Stop: Marseille
Saturday, September 26
Book your seat: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=793473&utm_source=external&utm_medium=referral&utm_campaign=shared

🇱🇧 Then, Lebanon
Saturday, October 17
Book your seat: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=793477&utm_source=external&utm_medium=referral&utm_campaign=shared

Optional wine pairings are available for both evenings. Seats are limited — reserve your spot and join us for the journey.

Our next Culinary Passport Dinner is this Saturday, August 22, and we’re officially fully booked! 🌎🍴For our guests who h...
08/18/2026

Our next Culinary Passport Dinner is this Saturday, August 22, and we’re officially fully booked! 🌎🍴

For our guests who have already secured their seats, here’s a look at the four-course menu awaiting you as we explore the flavors of Venezuela.

FIRST COURSE
Ceviche
Red Snapper, Shrimp, Charred Citrus, Tostones, Avocado, Red Onion, Red Bell Pepper, Cilantro Oil
Paired with Aveleda Alvarinho

SECOND COURSE
Arepa Trio
Lobster Reina Pepiada — Blue Corn, Avocado, Finger Lime, Pickled Shallot
Pork Belly Pabellón Criollo — Yellow Corn, Black Beans, Puffed Rice, Sweet Plantain Jam, Cotija Cheese
Oyster Mushroom — Red Corn, Leeks, Piquillo Peppers, Roasted Corn, Queso Asadero, Salsa de Ajo
Paired with Château des Jacques Clos des Jacques Chardonnay

THIRD COURSE
Asado Negro
48-Hour Braised Wagyu Beef Cheek, Long-Grain Rice, Caramelized Plantain Soubise, Carrot, Cashew Crumble
Paired with Château Chapelle d’Aliénor Bordeaux

FOURTH COURSE
Bienmesabe
Sponge Cake, Rum, Meringue, Coconut Custard Mousse, Passionfruit, Cinnamon Tuile
Paired with Villa Rosa Moscato d’Asti

We can’t wait to welcome everyone this Saturday for an evening of Venezuelan flavors, thoughtful wine pairings and culinary discovery. 🇻🇪✨

These dinners fill up quickly, and we’re working on the next Culinary Passport regions and dates now. We’ll share what’s next as soon as the details are ready!

Still thinking about our last Culinary Passport Dinner? So are we. 🌎✨As we look back on the incredible flavors and memor...
08/05/2026

Still thinking about our last Culinary Passport Dinner? So are we. 🌎✨

As we look back on the incredible flavors and memories from our Madagascar experience, we're already packing our bags for the next destination...

🇻🇪 Venezuela | Saturday, August 22

Join us for another unforgettable evening featuring a thoughtfully crafted multi-course menu inspired by the rich culinary traditions of Venezuela. From bold flavors to beautifully plated courses, every Culinary Passport Dinner offers a unique opportunity to experience the world—one destination at a time.

🍽️ Our full menu reveal is coming soon.

Reservations are now available, and seating is limited. Reserve your seat and continue the journey with us.
https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=736566&utm_source=external&utm_medium=referral&utm_campaign=shared

Join us this Saturday, July 25 at M Brothers as our Culinary Passport Dinner transports you to the island of Madagascar....
07/21/2026

Join us this Saturday, July 25 at M Brothers as our Culinary Passport Dinner transports you to the island of Madagascar. Experience a thoughtfully crafted multi-course menu inspired by the country's rich culinary heritage, where African, Asian, Indian, and French influences come together through vibrant spices, fresh ingredients, and unforgettable flavors.

From savory specialties to a decadent finale, this is a one-night-only dining experience you won't want to miss.

🍽️ Saturday, July 25
📍 M Brothers at Mayo
🎟️ Seating is limited—reserve your table today: https://www.opentable.com/booking/experiences-availability?rid=1215757&restref=1215757&experienceId=736561&utm_source=external&utm_medium=referral&utm_campaign=shared

A look back at our Culinary Passport journey to Greece 🇬🇷✨Vibrant Mediterranean flavors and thoughtfully paired wines, M...
06/04/2026

A look back at our Culinary Passport journey to Greece 🇬🇷✨

Vibrant Mediterranean flavors and thoughtfully paired wines, May's dinner transported guests to the sun-soaked shores of Greece for one unforgettable evening.

Thank you to everyone who joined us! Each Culinary Passport dinner is a celebration of culture, cuisine, and connection, and we're grateful to share these experiences with you.

Next stop: Sicily on June 27. 🌎🍷

Our next Culinary Passport destinations await! 🌎 Join us as we continue our 2026 Culinary Passport series with three new...
06/02/2026

Our next Culinary Passport destinations await! 🌎

Join us as we continue our 2026 Culinary Passport series with three new culinary adventures:

Sicily – June 27
Madagascar – July 25
Venezuela – August 22

Each one-night-only experience features a 4-course tasting menu inspired by the flavors, traditions, and ingredients of a different region of the world, with optional wine pairings available.

Reserve your seat through OpenTable. ✨

In observance of Memorial Day, M Brothers will be closed. If you’re at Mayo Clinic, stop by Zest for a quick and conveni...
05/25/2026

In observance of Memorial Day, M Brothers will be closed. If you’re at Mayo Clinic, stop by Zest for a quick and convenient refuel. Zest will be open regular hours.

Adventure, leisure, flavor ✈️🍷 Our Culinary Passport Dinners are monthly tasting experiences inspired by cuisines from a...
05/21/2026

Adventure, leisure, flavor ✈️🍷 Our Culinary Passport Dinners are monthly tasting experiences inspired by cuisines from around the world. Explore global flavors without ever leaving the comfort of Jacksonville.

Join us this Saturday for our Greece Culinary Passport Dinner, with upcoming destinations including Sicily, Venezuela, and more arriving this summer. Stay tuned for the full summer schedule and your next culinary escape.

Menu Reveal! 🇬🇷 Culinary Passport: Greece 🇬🇷Join us this Saturday, May 23, for our next Culinary Passport stop. Enjoy a ...
05/19/2026

Menu Reveal! 🇬🇷 Culinary Passport: Greece 🇬🇷

Join us this Saturday, May 23, for our next Culinary Passport stop. Enjoy a four-course tasting menu inspired by the Mediterranean, with wine pairings available to enhance your evening. Reservations are available at mnbrothersatmayo.com

Celebrating Nurses Week at M Brothers and Zest 💙We’re grateful to serve the incredible hospital staff at Mayo Clinic eve...
05/06/2026

Celebrating Nurses Week at M Brothers and Zest 💙

We’re grateful to serve the incredible hospital staff at Mayo Clinic every day and see firsthand the dedication, compassion, and hard work our nurses bring to every shift.

To say thank you, both concepts are offering 20% off for all nurses, May 6–May 12. Just show your badge at checkout.

From early mornings to late nights, your care makes a difference in so many lives, and we’re proud to celebrate you all week long.

Address

14335 Hospital Drive Suite 100
Jacksonville, FL
32224

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